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Thymic rejuvenation and the induction of tolerance by adult thymic grafts

The thymus, the site of origin of T cell immunity, shapes the repertoire of T cell reactivity through positive selection of developing T cells and prevents autoimmunity through negative selection of autoreactive T cells. Previous studies have demonstrated an important role for the thymus not only in...

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Autori principali: Nobori, Shuji, Shimizu, Akira, Okumi, Masayoshi, Samelson-Jones, Emma, Griesemer, Adam, Hirakata, Atsushi, Sachs, David H., Yamada, Kazuhiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1748180/
https://ncbi.nlm.nih.gov/pubmed/17148614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605159103
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