Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual-Targeting in Patient-Derived 3D Pancreatic Cancer Models

Pancreatic ductal adenocarcinoma (PDAC) is the 4(th) leading cause of cancer-related mortality in the United States. Aggressive treatment regimens have not changed the disease course, and the median survival has just recently reached a year. Several mechanisms are proposed to play a role in PDAC the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer Ther
Hauptverfasser: Logsdon, Derek P., Grimard, Michelle, Luo, Meihua, Shahda, Safi, Jiang, Yanlin, Tong, Yan, Yu, Zhangsheng, Zyromski, Nicholas, Schipani, Ernestina, Carta, Fabrizio, Supuran, Claudiu T., Korc, Murray, Ivan, Mircea, Kelley, Mark R., Fishel, Melissa L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097013/
https://ncbi.nlm.nih.gov/pubmed/27535970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0253
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge