Adventitial MSC-like cells are progenitors of vascular smooth muscle cells and drive vascular calcification in chronic kidney disease

Mesenchymal stem cell-like (MSC-like) cells reside in the vascular wall but their role in vascular regeneration and disease is poorly understood. Here, we show that Gli1(+) cells located in the arterial adventitia are progenitors of vascular smooth muscle cells, and contribute to neointima formation...

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Publicat a:Cell Stem Cell
Autors principals: Kramann, Rafael, Goettsch, Claudia, Wongboonsin, Janewit, Iwata, Hiroshi, Schneider, Rebekka K, Kuppe, Christoph, Kaesler, Nadine, Chang-Panesso, Monica, Machado, Flavia G., Gratwohl, Susannah, Madhurima, Kaushal, Hutcheson, Joshua D., Jain, Sanjay, Aikawa, Elena, Humphreys, Benjamin D.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097006/
https://ncbi.nlm.nih.gov/pubmed/27618218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.08.001
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