Sortilin mediates vascular calcification via its recruitment into extracellular vesicles

Vascular calcification is a common feature of major cardiovascular diseases. Extracellular vesicles participate in the formation of microcalcifications that are implicated in atherosclerotic plaque rupture; however, the mechanisms that regulate formation of calcifying extracellular vesicles remain o...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Goettsch, Claudia, Hutcheson, Joshua D., Aikawa, Masanori, Iwata, Hiroshi, Pham, Tan, Nykjaer, Anders, Kjolby, Mads, Rogers, Maximillian, Michel, Thomas, Shibasaki, Manabu, Hagita, Sumihiko, Kramann, Rafael, Rader, Daniel J., Libby, Peter, Singh, Sasha A., Aikawa, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811143/
https://ncbi.nlm.nih.gov/pubmed/26950419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80851
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