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p53‐dependent up‐regulation of CDKN1A and down‐regulation of CCNE2 in response to beryllium

OBJECTIVES: Beryllium salts (here, beryllium sulphate) can produce a cytostatic effect in some cell types. The basis for this effect may include increased expression of proliferation inhibitors, reduced expression of proliferation promoters, or both. This study sought to determine the role of p53, t...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Gorjala, P., Cairncross, J. G., Gary, R. K.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096984/
https://ncbi.nlm.nih.gov/pubmed/27611480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12291
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