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Down-Regulation of p53 by Double-Stranded RNA Modulates the Antiviral Response

p53 has been well characterized as a tumor suppressor gene, but its role in antiviral defense remains unclear. A recent report has demonstrated that p53 can be induced by interferons and is activated after vesicular stomatitis virus (VSV) infection. We observed that different nononcogenic viruses, i...

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Detalhes bibliográficos
Main Authors: Marques, Joao T., Rebouillat, Dominique, Ramana, Chilakamarti V., Murakami, Junko, Hill, Jason E., Gudkov, Andrei, Silverman, Robert H., Stark, George R., Williams, Bryan R. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193603/
https://ncbi.nlm.nih.gov/pubmed/16103161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.17.11105-11114.2005
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