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Bi-allelic Alteration and Dysregulation of the Hippo Pathway in Mucinous Tubular and Spindle Cell Carcinoma of the Kidney

Mucinous tubular and spindle cell carcinoma (MTSCC) is a relatively rare subtype of renal cell carcinoma with distinctive morphologic and cytogenetic features. Here we carry out whole exome and transcriptome sequencing of a multi-institutional cohort of MTSCC (n=22). We demonstrate the presence of e...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Mehra, Rohit, Vats, Pankaj, Cieslik, Marcin, Cao, Xuhong, Su, Fengyun, Shukla, Sudhanshu, Udager, Aaron M., Wang, Rui, Pan, Jincheng, Kasaian, Katayoon, Lonigro, Robert, Siddiqui, Javed, Premkumar, Kumpati, Palapattu, Ganesh, Weizer, Alon, Hafez, Khaled S., Wolf, J. Stuart, Sangoi, Ankur, Trpkov, Kiril, Osunkoya, Adeboye O., Zhou, Ming, Giannico, Giovanna, McKenney, Jesse K., Dhanasekaran, Saravana M., Chinnaiyan, Arul M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096979/
https://ncbi.nlm.nih.gov/pubmed/27604489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0267
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