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Helicase CHD4 is an epigenetic coregulator of PAX3-FOXO1 in alveolar rhabdomyosarcoma

A vast number of cancer genes are transcription factors that drive tumorigenesis as oncogenic fusion proteins. Although the direct targeting of transcription factors remains challenging, therapies aimed at oncogenic fusion proteins are attractive as potential treatments for cancer. There is particul...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Böhm, Maria, Wachtel, Marco, Marques, Joana G., Streiff, Natalie, Laubscher, Dominik, Nanni, Paolo, Mamchaoui, Kamel, Santoro, Raffaella, Schäfer, Beat W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096911/
https://ncbi.nlm.nih.gov/pubmed/27760049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85057
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