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Insulin receptor Thr(1160) phosphorylation mediates lipid-induced hepatic insulin resistance
Nonalcoholic fatty liver disease (NAFLD) is a risk factor for type 2 diabetes (T2D), but whether NAFLD plays a causal role in the pathogenesis of T2D is uncertain. One proposed mechanism linking NAFLD to hepatic insulin resistance involves diacylglycerol-mediated (DAG-mediated) activation of protein...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Clin Invest |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Clinical Investigation
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5096902/ https://ncbi.nlm.nih.gov/pubmed/27760050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI86013 |
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