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Hypoxia-inducible factors: a central link between inflammation and cancer

The tumor immune response is in a dynamic balance between antitumor mechanisms, which serve to decrease cancer growth, and the protumor inflammatory response, which increases immune tolerance, cell survival, and proliferation. Hypoxia and expression of HIF-1α and HIF-2α are characteristic features o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Triner, Daniel, Shah, Yatrik M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096825/
https://ncbi.nlm.nih.gov/pubmed/27525434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84430
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