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Hypoxia-Inducible Factors Link Iron Homeostasis and Erythropoiesis
Iron is required for efficient oxygen transport, and hypoxia signaling links erythropoiesis with iron homeostasis. Hypoxia induces a highly conserved signaling pathway in cells under conditions of low O(2). One component of this pathway, hypoxia-inducible factor (HIF), is a transcription factor that...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3943938/ https://ncbi.nlm.nih.gov/pubmed/24389303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.12.031 |
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