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Identification of the intermediate allosteric species in human hemoglobin reveals a molecular code for cooperative switching.

The 10 ligation species of human cyanomethemoglobin were previously found to distribute into three discrete cooperative free energy levels according to a combinatorial code (i.e., dependent on both the number and configuration of ligated subunits). Analysis of this distribution showed that the hemog...

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Detalhes bibliográficos
Main Authors: Daugherty, M A, Shea, M A, Johnson, J A, LiCata, V J, Turner, G J, Ackers, G K
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC50966/
https://ncbi.nlm.nih.gov/pubmed/1996311
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