Identification of the intermediate allosteric species in human hemoglobin reveals a molecular code for cooperative switching.

The 10 ligation species of human cyanomethemoglobin were previously found to distribute into three discrete cooperative free energy levels according to a combinatorial code (i.e., dependent on both the number and configuration of ligated subunits). Analysis of this distribution showed that the hemog...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Daugherty, M A, Shea, M A, Johnson, J A, LiCata, V J, Turner, G J, Ackers, G K
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1991
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1996311/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.4.1110
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