PARP10 deficiency manifests by infantile neurodegeneration and DNA repair defect

DNA repair mechanisms such as Nucleotide Excision Repair (NER) and Translesion Synthesis (TLS) are dependent on proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory protein. Recently, homozygosity for p.Ser228Ile mutation in the PCNA gene was reported in patients with neurodegenerat...

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Vydáno v:Neurogenetics
Hlavní autoři: Shahrour, Maher Awni, Nicolae, Claudia M., Edvardson, Simon, Ashhab, Motee, Galvan, Adri M., Constantin, Daniel, Abu-Libdeh, Bassam, Moldovan, George-Lucian, Elpeleg, Orly
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096377/
https://ncbi.nlm.nih.gov/pubmed/27624574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10048-016-0493-1
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