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Inhibition of the N-end rule pathway in living cells.

The N-end rule relates the metabolic stability of a protein to the identify of its amino-terminal residue. Previous work, using amino acid derivatives such as dipeptides to inhibit N-end rule-mediated protein degradation in an extract from mammalian reticulocytes, has demonstrated the existence of s...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Baker, R T, Varshavsky, A
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50962/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1899923/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.4.1090
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