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Inhibition of the N-end rule pathway in living cells.

The N-end rule relates the metabolic stability of a protein to the identify of its amino-terminal residue. Previous work, using amino acid derivatives such as dipeptides to inhibit N-end rule-mediated protein degradation in an extract from mammalian reticulocytes, has demonstrated the existence of s...

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Detalhes bibliográficos
Main Authors: Baker, R T, Varshavsky, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC50962/
https://ncbi.nlm.nih.gov/pubmed/1899923
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