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Dosing targeted and cytotoxic two‐drug combinations: Lessons learned from analysis of 24,326 patients reported 2010 through 2013

Combining agents has the potential to attenuate resistance in metastatic cancer. However, knowledge of appropriate starting doses for novel drug combinations in clinical trials and practice is lacking. Analysis of 372 published studies was used to ascertain safe starting doses for doublets involving...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Nikanjam, Mina, Liu, Sariah, Kurzrock, Razelle
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096042/
https://ncbi.nlm.nih.gov/pubmed/27389805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30262
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