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Dosing de novo combinations of two targeted drugs: Towards a customized precision medicine approach to advanced cancers

Metastatic cancers harbor complex genomic alterations. Thus, monotherapies are often suboptimal. Individualized combinations are needed in order to attenuate resistance. To help inform selection of safe starting doses for novel, two-agent, targeted drug combinations, we identified clinical trials in...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Oncotarget
मुख्य लेखकों: Liu, Sariah, Nikanjam, Mina, Kurzrock, Razelle
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Impact Journals LLC 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905475/
https://ncbi.nlm.nih.gov/pubmed/26824502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7023
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