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Dosing de novo combinations of two targeted drugs: Towards a customized precision medicine approach to advanced cancers

Metastatic cancers harbor complex genomic alterations. Thus, monotherapies are often suboptimal. Individualized combinations are needed in order to attenuate resistance. To help inform selection of safe starting doses for novel, two-agent, targeted drug combinations, we identified clinical trials in...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Sariah, Nikanjam, Mina, Kurzrock, Razelle
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905475/
https://ncbi.nlm.nih.gov/pubmed/26824502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7023
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