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The differential role of HTRA1 in HPV-positive and HPV-negative cervical cell line proliferation

BACKGROUND: High-risk human papillomaviruses (HPVs) are strongly associated with the development of some malignancies. The E6 and E7 viral oncoproteins are the primary proteins responsible for cell homeostasis alteration and immortalization. Furthermore, the E6 protein from high-risk HPVs can intera...

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Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Stuqui, Bruna, Conceição, André Luis Giacometti, Termini, Lara, Sichero, Laura, Villa, Luisa Lina, Rahal, Paula, Calmon, Marília de Freitas
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095955/
https://ncbi.nlm.nih.gov/pubmed/27809811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2873-1
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