The differential role of HTRA1 in HPV-positive and HPV-negative cervical cell line proliferation

BACKGROUND: High-risk human papillomaviruses (HPVs) are strongly associated with the development of some malignancies. The E6 and E7 viral oncoproteins are the primary proteins responsible for cell homeostasis alteration and immortalization. Furthermore, the E6 protein from high-risk HPVs can intera...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Stuqui, Bruna, Conceição, André Luis Giacometti, Termini, Lara, Sichero, Laura, Villa, Luisa Lina, Rahal, Paula, Calmon, Marília de Freitas
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095955/
https://ncbi.nlm.nih.gov/pubmed/27809811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2873-1
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