Efficacy of sacubitril/valsartan vs. enalapril at lower than target doses in heart failure with reduced ejection fraction: the PARADIGM‐HF trial

AIMS: In this analysis, we utilized data from PARADIGM‐HF to test the hypothesis that participants who exhibited any dose reduction during the trial would have similar benefits from lower doses of sacubitril/valsartan relative to lower doses of enalapril. METHODS AND RESULTS: In a post‐hoc analysis...

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Detalles Bibliográficos
Publicado en:Eur J Heart Fail
Autores principales: Vardeny, Orly, Claggett, Brian, Packer, Milton, Zile, Michael R., Rouleau, Jean, Swedberg, Karl, Teerlink, John R., Desai, Akshay S., Lefkowitz, Martin, Shi, Victor, McMurray, John J.V., Solomon, Scott D.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley & Sons, Ltd 2016
Materias:
Medical Treatment
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095784/
https://ncbi.nlm.nih.gov/pubmed/27283779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejhf.580
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