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C1q and HMGB1 reciprocally regulate human macrophage polarization

A healthy immune system results from a balance of stimulatory and inhibitory pathways that allow effective responses to acute insults, without descending into chronic inflammation. Failed homeostasis is characteristic of autoimmune diseases such as systemic lupus erythematosus. Although HMGB1 induce...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Son, Myoungsun, Porat, Amit, He, Mingzhu, Suurmond, Jolien, Santiago-Schwarz, Frances, Andersson, Ulf, Coleman, Thomas R., Volpe, Bruce T., Tracey, Kevin J., Al-Abed, Yousef, Diamond, Betty
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095756/
https://ncbi.nlm.nih.gov/pubmed/27683415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-05-719757
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