C1q and HMGB1 reciprocally regulate human macrophage polarization

A healthy immune system results from a balance of stimulatory and inhibitory pathways that allow effective responses to acute insults, without descending into chronic inflammation. Failed homeostasis is characteristic of autoimmune diseases such as systemic lupus erythematosus. Although HMGB1 induce...

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Bibliographic Details
Published in:Blood
Main Authors: Son, Myoungsun, Porat, Amit, He, Mingzhu, Suurmond, Jolien, Santiago-Schwarz, Frances, Andersson, Ulf, Coleman, Thomas R., Volpe, Bruce T., Tracey, Kevin J., Al-Abed, Yousef, Diamond, Betty
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2016
Subjects:
Immunobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095756/
https://ncbi.nlm.nih.gov/pubmed/27683415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-05-719757
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