Notch-1 Confers Chemoresistance in Lung Adenocarcinoma to Taxanes through AP-1/microRNA-451 Mediated Regulation of MDR-1

We previously demonstrated that expression of Notch-1 is associated with poor prognosis in lung adenocarcinoma (LAD) patients. The aim of this study is to reveal whether Notch-1 was associated with Taxanes-resistant LAD and, the underlying mechanisms. We collected 39 patients of advanced LAD treated...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Huang, Jiayuan, Chen, Yitian, Li, Junyang, Zhang, Kai, Chen, Jing, Chen, Dongqin, Feng, Bing, Song, Haizhu, Feng, Jifeng, Wang, Rui, Chen, Longbang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095685/
https://ncbi.nlm.nih.gov/pubmed/27727250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.82
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