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LncRNA SNHG15 regulates EGFR-TKI acquired resistance in lung adenocarcinoma through sponging miR-451 to upregulate MDR-1

Lung adenocarcinoma (LUAD) is the main component of non-small-cell lung cancer (NSCLC) and causes a great health concern globally. The top priority of LUAD treatment is to deal with gefitinib resistance. Long non-coding RNAs are certified to modify gefitinib resistance in the course of tumor aggrava...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Huang, Jiayuan, Pan, Banzhou, Xia, Guohao, Zhu, Jingni, Li, Chenchen, Feng, Jifeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354989/
https://ncbi.nlm.nih.gov/pubmed/32655137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2683-x
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