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Elevated homocysteine levels in type 2 diabetes induce constitutive neutrophil extracellular traps

Constitutively active neutrophil extracellular traps (NETs) and elevated plasma homocysteine are independent risk factors for Type 2 Diabetes (T2D) associated vascular diseases. Here, we show robust NETosis due to elevated plasma homocysteine levels in T2D subjects and increased components of NETs s...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Joshi, Manjunath B, Baipadithaya, Guruprasad, Balakrishnan, Aswath, Hegde, Mangala, Vohra, Manik, Ahamed, Rayees, Nagri, Shivashankara K, Ramachandra, Lingadakai, Satyamoorthy, Kapaettu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095649/
https://ncbi.nlm.nih.gov/pubmed/27811985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36362
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