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Expression patterns of Ikaros family members during positive selection and lineage commitment of human thymocytes

The Ikaros family of transcription factors is essential for normal T‐cell development, but their expression pattern in human thymocytes remains poorly defined. Our goal is to determine how protein levels of Ikaros, Helios and Aiolos change as human thymocytes progress through the positive selection...

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Publicat a:Immunology
Autors principals: Mitchell, Julie L., Seng, Amara, Yankee, Thomas M.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095499/
https://ncbi.nlm.nih.gov/pubmed/27502439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12657
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