IL-1β, But Not Programed Death-1 and Programed Death Ligand Pathway, Is Critical for the Human Th17 Response to Mycobacterium tuberculosis

The programed death-1 (PD-1)–programed death ligand-1 (PD-L1) and PD-L2 co-inhibitory pathway has been implicated in the evasion strategies of Mycobacterium tuberculosis. Specifically, M. tuberculosis-induced PD-L1 orchestrates expansion of regulatory T cells and suppression of Th1 response. However...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Stephen-Victor, Emmanuel, Sharma, Varun Kumar, Das, Mrinmoy, Karnam, Anupama, Saha, Chaitrali, Lecerf, Maxime, Galeotti, Caroline, Kaveri, Srinivas V., Bayry, Jagadeesh
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095489/
https://ncbi.nlm.nih.gov/pubmed/27867382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00465
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