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MyD88 Adapter-like (Mal)/TIRAP Is Required for Cytokine Production by Splenic Ly6C(lo)TLR2(hi) but Not by Ly6C(hi)TLR2(hi) Monocytes during Trypanosoma cruzi Infection

This study continues to explore the plasticity of Toll-like receptor 2 (TLR2) previously described in immune response during Trypanosoma cruzi infection. Here, we have shown that Ly6C(hi)TLR2(hi) monocytes were involved in TNF-α and IL-12 production, whereas Ly6C(lo)TLR2(hi) monocytes were mainly co...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Gravina, Humberto Doriguêtto, Goes, Alfredo Miranda, Murta, Silvane Maria Fonseca, Ropert, Catherine
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095435/
https://ncbi.nlm.nih.gov/pubmed/27646001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.729509
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