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Investigation of interactions between TLR2, MyD88 and TIRAP by bioluminescence resonance energy transfer is hampered by artefacts of protein overexpression

Toll like receptors (TLRs) are important pattern recognition receptors that can detect pathogen and danger associated molecular patterns to initiate an innate immune response. TLR1 and 2 heterodimerize at the plasma membrane upon binding to triacylated lipopeptides from bacterial cell walls, or to t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sampaio, Natália G., Kocan, Martina, Schofield, Louis, Pfleger, Kevin D. G., Eriksson, Emily M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107161/
https://ncbi.nlm.nih.gov/pubmed/30138457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202408
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