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Baclofen Protects Primary Rat Retinal Ganglion Cells from Chemical Hypoxia-Induced Apoptosis Through the Akt and PERK Pathways

Retinal ganglion cells (RGCs) consume large quantities of energy to convert light information into a neuronal signal, which makes them highly susceptible to hypoxic injury. This study aimed to investigate the potential protection by baclofen, a GABA(B) receptor agonist of RGCs against hypoxia-induce...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Fu, Pingping, Wu, Qiang, Hu, Jianyan, Li, Tingting, Gao, Fengjuan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095369/
https://ncbi.nlm.nih.gov/pubmed/27867349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00255
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