AMPK-mediated cardioprotection of atorvastatin relates to the reduction of apoptosis and activation of autophagy in infarcted rat hearts

Atorvastatin (ATV) has an important pro-survival role in cardiomyocytes after acute myocardial infarction (AMI). The objectives of this study were to: 1) determine whether ATV could affect autophagy of cardiomyocytes via the AMP-activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR) pa...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Li, Qing, Dong, Qiu-Ting, Yang, Yue-Jin, Tian, Xia-Qiu, Jin, Chen, Huang, Pei-Sen, Jiang, Lei-Pei, Chen, Gui-Hao
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095309/
https://ncbi.nlm.nih.gov/pubmed/27830000
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