HMGB1-TLR4 signaling participates in renal ischemia reperfusion injury and could be attenuated by dexamethasone-mediated inhibition of the ERK/NF-κB pathway

Studies have shown that the HMGB1-TLR4 (High-mobility group protein B1, toll-like receptor 4) pathway participates in renal ischemic reperfusion injury (IRI) and that dexamethasone (DEX) could protect the kidney against IRI. This study aims to examine the protective effects of DEX on renal IRI and f...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Zhang, Jiong, Xia, Jumei, Zhang, Ying, Xiao, Fang, Wang, Jin, Gao, Hongyu, Liu, Yanyan, Rong, Song, Yao, Ying, Xu, Gang, Li, Junhua
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095301/
https://ncbi.nlm.nih.gov/pubmed/27829992
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