Aucubin Attenuates Liver Ischemia-Reperfusion Injury by Inhibiting the HMGB1/TLR-4/NF-κB Signaling Pathway, Oxidative Stress, and Apoptosis

Liver ischemia-reperfusion injury (IRI) is a common clinical event with high morbidity in patients undergoing complex liver surgery or having abdominal trauma. Inflammatory and oxidative stress responses are the main contributing factors in liver IRI. The iridoid glucoside aucubin (AU) has good anti...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zhang, Shilong, Feng, Zanjie, Gao, Weidong, Duan, Yuling, Fan, Guoxin, Geng, Xin, Wu, Bo, Li, Kai, Liu, Kangwei, Peng, Cijun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7506056/
https://ncbi.nlm.nih.gov/pubmed/33013386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.544124
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