Recombinant fusion protein identified by lepromatous sera mimics native Mycobacterium leprae in T-cell responses across the leprosy spectrum.

Pooled polyvalent sera from lepromatous leprosy patients were used to screen a lambda gt11 recombinant DNA expression library of Mycobacterium leprae in order to identify the relevant antigens recognized by the human immune response. Of the 300,000 phages screened, 4 clones were identified that code...

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Dettagli Bibliografici
Autori principali: Laal, S, Sharma, Y D, Prasad, H K, Murtaza, A, Singh, S, Tangri, S, Misra, R S, Nath, I
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1991
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC50953/
https://ncbi.nlm.nih.gov/pubmed/1992456
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