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Suppression of GLI sensitizes medulloblastoma cells to mitochondria-mediated apoptosis
PURPOSE: The sonic hedgehog (SHH) signalling pathway plays the important role in medulloblastoma (MB). Altered GLI expression plays a key role in these processes, and the inhibition of GLI may be a good cancer-targeted therapy. This study aimed to investigate whether GANT61, a GLI inhibitor, may inh...
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| Publicado no: | J Cancer Res Clin Oncol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5095157/ https://ncbi.nlm.nih.gov/pubmed/27601167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-016-2241-1 |
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