C-terminus of MUC16 activates Wnt signaling pathway through its interaction with β-catenin to promote tumorigenesis and metastasis

MUC16/CA125 has been identified as a prominent cancer biomarker, especially for epithelial ovarian cancers, in clinical test for over three decades. Due to its huge mass, limited knowledge of MUC16 was acquired previously. By utilizing a well characterized self-made MUC16 monoclonal antibody, we ide...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Qi, Cheng, Zhen, Luo, Lianzhong, Yang, Yun, Zhang, Zhenzhu, Ma, Huanhuan, Chen, Tao, Huang, Xi, Lin, Shu-Yong, Jin, Meijun, Li, Qinxi, Li, Xiaotong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095040/
https://ncbi.nlm.nih.gov/pubmed/27167110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9191
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