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Matricellular protein CCN1 mediates doxorubicin-induced cardiomyopathy in mice

Doxorubicin (DOX) is an effective chemotherapeutic agent however its clinical use is limited by its cumulative cardiotoxicity. Matricellular protein CCN1 mediates work-overload-induced cardiac injury. We aimed to assess the role of CCN1 in DOX-associated cardiomyopathy. Here we discovered CCN1 expre...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hsu, Pei-Ling, Mo, Fan-E
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095032/
https://ncbi.nlm.nih.gov/pubmed/27167338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9162
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