Relative telomere lengths in tumor and normal mucosa are related to disease progression and chromosome instability profiles in colorectal cancer

Telomeric dysfunction is linked to colorectal cancer (CRC) initiation. However, the relationship of normal tissue and tumor telomere lengths with CRC progression, molecular features and prognosis is unclear. Here, we measured relative telomere length (RTL) by real-time quantitative PCR in 90 adenoma...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Suraweera, Nirosha, Mouradov, Dmitri, Li, Shan, Jorissen, Robert N., Hampson, Debbie, Ghosh, Anil, Sengupta, Neel, Thaha, Mohamed, Ahmed, Shafi, Kirwan, Michael, Aleva, Floor, Propper, David, Feakins, Roger M., Vulliamy, Tom, Elwood, Ngaire J., Tian, Pei, Ward, Robyn L., Hawkins, Nicholas J., Xu, Zheng-Zhou, Molloy, Peter L., Jones, Ian T., Croxford, Matthew, Gibbs, Peter, Silver, Andrew, Sieber, Oliver M.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095014/
https://ncbi.nlm.nih.gov/pubmed/27167335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9015
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