Relative telomere lengths in tumor and normal mucosa are related to disease progression and chromosome instability profiles in colorectal cancer

Telomeric dysfunction is linked to colorectal cancer (CRC) initiation. However, the relationship of normal tissue and tumor telomere lengths with CRC progression, molecular features and prognosis is unclear. Here, we measured relative telomere length (RTL) by real-time quantitative PCR in 90 adenoma...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Suraweera, Nirosha, Mouradov, Dmitri, Li, Shan, Jorissen, Robert N., Hampson, Debbie, Ghosh, Anil, Sengupta, Neel, Thaha, Mohamed, Ahmed, Shafi, Kirwan, Michael, Aleva, Floor, Propper, David, Feakins, Roger M., Vulliamy, Tom, Elwood, Ngaire J., Tian, Pei, Ward, Robyn L., Hawkins, Nicholas J., Xu, Zheng-Zhou, Molloy, Peter L., Jones, Ian T., Croxford, Matthew, Gibbs, Peter, Silver, Andrew, Sieber, Oliver M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095014/
https://ncbi.nlm.nih.gov/pubmed/27167335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9015
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