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Temporal and spatial patterns of transgene expression in aging adult mice provide insights about the origins, organization, and differentiation of the intestinal epithelium.

We have used liver fatty acid-binding protein/human growth hormone (L-FABP/hGH) fusion genes to explore the temporal and spatial differentiation of intestinal epithelial cells in 1- to 12-month-old transgenic mice. The intact, endogenous L-FABP gene (Fabpl) was not expressed in the colon at any time...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Cohn, S M, Roth, K A, Birkenmeier, E H, Gordon, J I
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50949/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1992454/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.3.1034
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