The basic helix–loop–helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression

The gene encoding the hormone secretin is expressed only in enteroendocrine S cells and insulin-producing pancreatic β cells during development. A 120-bp enhancer directs cell-specific expression of the rat secretin gene in secretin-expressing cells. The enhancer includes an E-box sequence, CAGCTG,...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Mutoh, Hiroyuki, Fung, Brenda P., Naya, Francisco J., Tsai, Ming-Jer, Nishitani, Junko, Leiter, Andrew B.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20478/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9108015/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.8.3560
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