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The basic helix–loop–helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression

The gene encoding the hormone secretin is expressed only in enteroendocrine S cells and insulin-producing pancreatic β cells during development. A 120-bp enhancer directs cell-specific expression of the rat secretin gene in secretin-expressing cells. The enhancer includes an E-box sequence, CAGCTG,...

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Detalhes bibliográficos
Main Authors: Mutoh, Hiroyuki, Fung, Brenda P., Naya, Francisco J., Tsai, Ming-Jer, Nishitani, Junko, Leiter, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20478/
https://ncbi.nlm.nih.gov/pubmed/9108015
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