A computational approach to map nucleosome positions and alternative chromatin states with base pair resolution

Understanding chromatin function requires knowing the precise location of nucleosomes. MNase-seq methods have been widely applied to characterize nucleosome organization in vivo, but generally lack the accuracy to determine the precise nucleosome positions. Here we develop a computational approach l...

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Bibliographic Details
Published in:eLife
Main Authors: Zhou, Xu, Blocker, Alexander W, Airoldi, Edoardo M, O'Shea, Erin K
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2016
Subjects:
Computational and Systems Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094857/
https://ncbi.nlm.nih.gov/pubmed/27623011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16970
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