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A computational approach to map nucleosome positions and alternative chromatin states with base pair resolution
Understanding chromatin function requires knowing the precise location of nucleosomes. MNase-seq methods have been widely applied to characterize nucleosome organization in vivo, but generally lack the accuracy to determine the precise nucleosome positions. Here we develop a computational approach l...
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Publicado no: | eLife |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
eLife Sciences Publications, Ltd
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5094857/ https://ncbi.nlm.nih.gov/pubmed/27623011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16970 |
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