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A Mutational Hotspot and Strong Selection Contribute to the Order of Mutations Selected for during Escherichia coli Adaptation to the Gut

The relative role of drift versus selection underlying the evolution of bacterial species within the gut microbiota remains poorly understood. The large sizes of bacterial populations in this environment suggest that even adaptive mutations with weak effects, thought to be the most frequently occurr...

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Pubblicato in:PLoS Genet
Autori principali: Lourenço, Marta, Ramiro, Ricardo S., Güleresi, Daniela, Barroso-Batista, João, Xavier, Karina B., Gordo, Isabel, Sousa, Ana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094792/
https://ncbi.nlm.nih.gov/pubmed/27812114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006420
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