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The First Steps of Adaptation of Escherichia coli to the Gut Are Dominated by Soft Sweeps

The accumulation of adaptive mutations is essential for survival in novel environments. However, in clonal populations with a high mutational supply, the power of natural selection is expected to be limited. This is due to clonal interference - the competition of clones carrying different beneficial...

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Hlavní autoři: Barroso-Batista, João, Sousa, Ana, Lourenço, Marta, Bergman, Marie-Louise, Sobral, Daniel, Demengeot, Jocelyne, Xavier, Karina B., Gordo, Isabel
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945185/
https://ncbi.nlm.nih.gov/pubmed/24603313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004182
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