Cathelicidin Insufficiency in Patients with Fatal Leptospirosis

Leptospirosis causes significant morbidity and mortality worldwide; however, the role of the host immune response in disease progression and high case fatality (>10–50%) is poorly understood. We conducted a multi-parameter investigation of patients with acute leptospirosis to identify mechanisms...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Lindow, Janet C., Wunder, Elsio A., Popper, Stephen J., Min, Jin-na, Mannam, Praveen, Srivastava, Anup, Yao, Yi, Hacker, Kathryn P., Raddassi, Khadir, Lee, Patty J., Montgomery, Ruth R., Shaw, Albert C., Hagan, Jose E., Araújo, Guilherme C., Nery, Nivison, Relman, David A., Kim, Charles C., Reis, Mitermayer G., Ko, Albert I.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094754/
https://ncbi.nlm.nih.gov/pubmed/27812211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005943
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