Distinct antibody responses of patients with mild and severe leptospirosis determined by whole proteome microarray analysis

BACKGROUND: Leptospirosis is an important zoonotic disease worldwide. Humans usually present a mild non-specific febrile illness, but a proportion of them develop more severe outcomes, such as multi-organ failure, lung hemorrhage and death. Such complications are thought to depend on several factors...

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Foilsithe in:PLoS Negl Trop Dis
Main Authors: Lessa-Aquino, Carolina, Lindow, Janet C., Randall, Arlo, Wunder, Elsio, Pablo, Jozelyn, Nakajima, Rie, Jasinskas, Algis, Cruz, Jaqueline S., Damião, Alcineia O., Nery, Nívison, Ribeiro, Guilherme S., Costa, Federico, Hagan, José E., Reis, Mitermayer Galvão, Ko, Albert I., Medeiros, Marco Alberto, Felgner, Philip L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302828/
https://ncbi.nlm.nih.gov/pubmed/28141801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005349
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