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Distinct antibody responses of patients with mild and severe leptospirosis determined by whole proteome microarray analysis

BACKGROUND: Leptospirosis is an important zoonotic disease worldwide. Humans usually present a mild non-specific febrile illness, but a proportion of them develop more severe outcomes, such as multi-organ failure, lung hemorrhage and death. Such complications are thought to depend on several factors...

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Bibliografiset tiedot
Julkaisussa:PLoS Negl Trop Dis
Päätekijät: Lessa-Aquino, Carolina, Lindow, Janet C., Randall, Arlo, Wunder, Elsio, Pablo, Jozelyn, Nakajima, Rie, Jasinskas, Algis, Cruz, Jaqueline S., Damião, Alcineia O., Nery, Nívison, Ribeiro, Guilherme S., Costa, Federico, Hagan, José E., Reis, Mitermayer Galvão, Ko, Albert I., Medeiros, Marco Alberto, Felgner, Philip L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302828/
https://ncbi.nlm.nih.gov/pubmed/28141801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005349
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