Visceral Adipose MicroRNA 223 Is Upregulated in Human and Murine Obesity and Modulates the Inflammatory Phenotype of Macrophages

Obesity in humans and mice is typified by an activated macrophage phenotype in the visceral adipose tissue (VAT) leading to increased macrophage-mediated inflammation. microRNAs (miRNAs) play an important role in regulating inflammatory pathways in macrophages, and in this study we compared miRNA ex...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Deiuliis, Jeffrey A., Syed, Rafay, Duggineni, Dheeraj, Rutsky, Jessica, Rengasamy, Palanivel, Zhang, Jie, Huang, Kun, Needleman, Bradley, Mikami, Dean, Perry, Kyle, Hazey, Jeffrey, Rajagopalan, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094706/
https://ncbi.nlm.nih.gov/pubmed/27812198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165962
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