Visceral Adipose MicroRNA 223 Is Upregulated in Human and Murine Obesity and Modulates the Inflammatory Phenotype of Macrophages

Obesity in humans and mice is typified by an activated macrophage phenotype in the visceral adipose tissue (VAT) leading to increased macrophage-mediated inflammation. microRNAs (miRNAs) play an important role in regulating inflammatory pathways in macrophages, and in this study we compared miRNA ex...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Deiuliis, Jeffrey A., Syed, Rafay, Duggineni, Dheeraj, Rutsky, Jessica, Rengasamy, Palanivel, Zhang, Jie, Huang, Kun, Needleman, Bradley, Mikami, Dean, Perry, Kyle, Hazey, Jeffrey, Rajagopalan, Sanjay
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094706/
https://ncbi.nlm.nih.gov/pubmed/27812198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165962
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