Visceral Adipose Inflammation in Obesity Is Associated with Critical Alterations in Tregulatory Cell Numbers

BACKGROUND: The development of insulin resistance (IR) in mouse models of obesity and type 2 diabetes mellitus (DM) is characterized by progressive accumulation of inflammatory macrophages and subpopulations of T cells in the visceral adipose. Regulatory T cells (Tregs) may play a critical role in m...

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Autori principali: Deiuliis, Jeffrey, Shah, Zubair, Shah, Nilay, Needleman, Bradley, Mikami, Dean, Narula, Vimal, Perry, Kyle, Hazey, Jeffrey, Kampfrath, Thomas, Kollengode, Madhukar, Sun, Qinghua, Satoskar, Abhay R., Lumeng, Carey, Moffatt-Bruce, Susan, Rajagopalan, Sanjay
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3027666/
https://ncbi.nlm.nih.gov/pubmed/21298111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016376
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