Functional variants of human papillomavirus type 16 demonstrate host genome integration and transcriptional alterations corresponding to their unique cancer epidemiology

BACKGROUND: Human papillomaviruses (HPVs) are a worldwide burden as they are a widespread group of tumour viruses in humans. Having a tropism for mucosal tissues, high-risk HPVs are detected in nearly all cervical cancers. HPV16 is the most common high-risk type but not all women infected with high-...

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發表在:BMC Genomics
Main Authors: Jackson, Robert, Rosa, Bruce A., Lameiras, Sonia, Cuninghame, Sean, Bernard, Josee, Floriano, Wely B., Lambert, Paul F., Nicolas, Alain, Zehbe, Ingeborg
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094076/
https://ncbi.nlm.nih.gov/pubmed/27806689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3203-3
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