Cardioprotective effects of thioredoxin in myocardial ischemia and the reperfusion role of S-nitrosation

Apoptosis contributes to myocardial ischemia/reperfusion (MI/R) injury, and both thioredoxin (Trx) and nitric oxide have been shown to exert antiapoptotic effects in vitro. Recent evidence suggests that this particular action of Trx requires S-nitrosation at Cys-69. The present study sought to inves...

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Autori principali: Tao, Ling, Gao, Erhe, Bryan, Nathan S., Qu, Yan, Liu, Hui-Rong, Hu, Aihua, Christopher, Theodore A., Lopez, Bernard L., Yodoi, Junji, Koch, Walter J., Feelisch, Martin, Ma, Xin L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC509224/
https://ncbi.nlm.nih.gov/pubmed/15277664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402941101
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